Inclusion Criteria:

•A male or female between 15 and 50 years of age at the time of the first vaccination.
•Free of obvious health problems as established by medical history and clinical examination before entering into the study.
•Written informed consent obtained from the subject and/or from the parents or guardians of the subject.
•If the subject is female, she must be of non-childbearing potential, or, if of childbearing potential, she must be abstinent or use adequate contraceptive precautions for one month prior to vaccination and up to two months after the last vaccination



Exclusion Criteria:

•Use of any investigational or non-registered drug or vaccine other than the study vaccine(s) during the study period or within 30 days preceding the first dose of study vaccine.
•Administration of chronic (defined as more than 14 days) immunosuppressants or other immune-modifying drugs within six months of vaccination.
•Planned administration/ administration of a vaccine not foreseen by the study protocol during the period starting from 30 days before each dose of vaccine and ending 30 days after.
•Previous vaccination against hepatitis B.
•History of significant and persisting hematological, hepatic, renal, cardiac or respiratory disease.
•Any confirmed or suspected immunosuppressive or immunodeficient condition, including human immunodeficiency virus (HIV) infection.
•A family history of congenital or hereditary immunodeficiency.
•History of allergic disease or reactions likely to be exacerbated by any component of the vaccine.
•Acute disease at the time of enrollment.
•Hepatomegaly, right upper quadrant abdominal pain or tenderness.
•Oral temperature of ≥37.5°C (99.5°F).
•Administration of immunoglobulins and/or any blood products within the three months preceding the first dose of study vaccine or planned administration/ administration during the study period.
•Pregnant or lactating female.
•History of chronic alcohol consumption and/or intravenous drug abuse