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Result Summary for 114009

Result Summary
Protocol ID: 114009
Clinical Study ID: SIR114009
Official Title: A Phase I study to evaluate single and multiple (seven) oral doses of SRT2104 on the endotoxin induced inflammatory response in healthy male subjects
Phase: phase 1
Study Indications or Diseases:
  • Sepsis
Generic Name: SRT2104
Trade/Product Name: SRT2104
Approved Drug Label: http://www.gsk.com/products.html
Results Summary: Click here to download result summary. Click here to download result summary.
Citations:
  • van der meer, AJ, Scicluno, B, Lin, J, Jacobson, EW, Vlasuk, GP, van der Poll. The first demonstration of clinical activity by a small molcule SIRT1 activator: SRT 2104 reduces cytokine release and coagulation activation in a human enotoxin model. [Inflammation Research]. 2011;60(Supplement 1):S1-321.

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