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Result Summary for APV30002

Result Summary

Protocol ID:	APV30002
Clinical Study ID:	APV30002
Official Title:	A Randomized, Open-Label, Two Arm Trial to Compare the Safety and Antiviral Efficacy of GW433908/Ritonavir QD to Nelfinavir BID When Used in Combination with Abacavir and Lamivudine BID for 48 Weeks in Antiretroviral Therapy Naïve HIV-1 Infected Subjects
Phase:	Phase 3
Study Indications or Diseases:	Infection, Human Immunodeficiency Virus I
Generic Name:	fosamprenavir
Trade/Product Name:	lexiva;lexiva
Approved Drug Label:	http://www.gsk.com/products.html
Results Summary:	Click here to download result summary.
Citations:	Abstract: First report of development of resistance to boosted fosamprenavir in an art-naive subject: virologic and clinical outcome. SAX, P. E. , XU, F. , TISDALE, M. , and ELSTON, R. 45th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) 9/21/2005 New Orleans, LA; USA Gathe JC, Ive P, Wood R, et al. SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir/ritonavir versus twice-daily nelfinavir in naive HIV-1 infected patients. AIDS 2004;18(11):1529-37. MacManus S, Yates P, Elston RC, White S, Richards N, Snowden W. GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: Absence of protease resistance at 48 weeks. AIDS 2004;18:651-55. Abstract: Sustained virologic and immunologic response over 120 weeks in antiretroviral therapy (art)-naive subjects receiving fosamprenavir/ ritonavir (fpv/r) qd. Scharmann, D. 1, Gathe, J. , Wood, R. , Bellos, N. , Stark, T. , Thomas, D. , Garris, C. , and Rockstroh, J. 10. Deutscher und 16. Österreichischer Aids-Kongress 6/1/2005 Wien; Austria Abstract: Safety of a fosamprenavir/ritonavir (fpv/r) containing regimen over 120 weeks in hiv-1 infected therapy-naive adults with or without hepatitis b (hbv) and/or c (hcv) co-infection. DeJesus, E. , Gladysz, A. , Vera, J. , Pulido, F. , Carosi, G. , Garris, C. , Givens, N. , Yeo, J. , and Felton, M. 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment 7/24/2005 Rio de Janeiro; Brazil