Pre-Clinical Publications

 

This section of the GSK study register provides citations from pre-clinical research where there is a GSK author. Please note that there may be other publications that are not listed here.

To find citations, enter a key word into the Citation Text Search field and/or enter a Publication Year.

 

 

Publication Year Citation
2016 Abrahams KA, Chung CW, Ghidelli-Disse S, et al. Identification of KasA as the cellular target of an anti-tubercular scaffold. Nat Commun. 2016;7:12581.
2016 Adams PD, Aertgeerts K, Bauer C, et al. Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop. Structure. 2016;24(4):502-508.
2016 Aich U, Lakbub J, Liu A. State-of-the-art technologies for rapid and high-throughput sample preparation and analysis of N-glycans from antibodies. Electrophoresis. 2016;37(11):1468-1488.
2016 Alamillo-Ferrer C, Karabourniotis-Sotti M, Kennedy AR, Campbell M, Tomkinson NC. Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of gamma-Lactones, Isobenzofuranones, and Tetrahydrofurans. Org Lett. 2016;18(13):3102-3105.
2016 Alder CM, Hayler JD, Henderson RK, et al. Updating and further expanding GSK's solvent sustainability guide. Green Chemistry. 2016;18(13):3879-3890.
2016 Allen DW. Phosphines and related C-P bonded compounds. In: Allen DW, Tebby JC, Loakes D, eds. Organophosphorus Chemistry. Vol 45: Royal Society of Chemistry; 2016:1-50.
2016 Amata E, Xi H, Colmenarejo G, et al. Identification of "Preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing? ACS Infect Dis. 2016;2(3):180-186.
2016 Anderson JC, Campbell IB, Campos S, et al. Reductive conjugate addition nitro-Mannich route for the stereoselective synthesis of 1,2,3,4-tetrahydroquinoxalines. Org Biomol Chem. 2016;14(35):8270-8277.
2016 Anderson NA, Campbell IB, Fallon BJ, et al. Synthesis and determination of absolute configuration of a non-peptidic alphavbeta6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. Org Biomol Chem. 2016;14(25):5992-6009.
2016 Aon JC, Sun J, Leighton JM, Appelbaum ER. Hypoxia-elicited impairment of cell wall integrity, glycosylation precursor synthesis, and growth in scaled-up high-cell density fed-batch cultures of Saccharomyces cerevisiae. Microb Cell Fact. 2016;15(1):142.
2016 Archibald PR, Chandra A, Thomas D, et al. Comparability of automated human induced pluripotent stem cell culture: a pilot study. Bioprocess Biosyst Eng. 2016;39(12):1847-1858.
2016 Arico-Muendel CC. From haystack to needle: finding value with DNA encoded library technology at GSK. MedChemComm. 2016;7(10):1898-1909.
2016 Bahamontes-Rosa N, Alejandre AR, Gomez V, et al. New molecular settings to support in vivo anti-malarial assays. Malar J. 2016;15:147.
2016 Bahamontes-Rosa N, Gomez-Lorenzo MG, Lelievre J, et al. A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents. Malar J. 2016;15(1):385.
2016 Ball AL, Kamalian L, Alfirevic A, Lyon JJ, Chadwick AE. Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells. Toxicol Sci. 2016;153(2):341-351.
2016 Bamborough P, Chung CW, Demont EH, et al. A Chemical Probe for the ATAD2 Bromodomain. Angew Chem Int Ed Engl. 2016;55(38):11382-11386.
2016 Bandichhor R, Bhattacharya A, Bryan MC, et al. Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. 2016;20(7):1118-1132.
2016 Bao J, Krylova SM, Cherney LT, et al. Predicting Electrophoretic Mobility of Protein-Ligand Complexes for Ligands from DNA-Encoded Libraries of Small Molecules. Anal Chem. 2016;88(10):5498-5506.
2016 Barham JP, Coulthard G, Emery KJ, et al. KOtBu: A Privileged Reagent for Electron Transfer Reactions? J Am Chem Soc. 2016;138(23):7402-7410.
2016 Barham JP, Coulthard G, Kane RG, Delgado N, John MP, Murphy JA. Double Deprotonation of Pyridinols Generates Potent Organic Electron-Donor Initiators for Haloarene-Arene Coupling. Angew Chem Int Ed Engl. 2016;55(14):4492-4496.
2016 Barham JP, John MP, Murphy JA. Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C-H Functionalization of Trialkylamine N-CH3 Groups. J Am Chem Soc. 2016;138(47):15482-15487.
2016 Bate ST, Chatfield MJ. Identifying the structure of the experimental design. J Qual Technol. 2016;48(4):343-364.
2016 Bate ST, Chatfield MJ. Using the structure of the experimental design and the randomization to construct a mixed model. J Qual Technol. 2016;48(4):365-387.
2016 Batt SM, Cacho Izquierdo M, Castro Pichel J, et al. Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-beta-d-ribose Oxidase. ACS Infect Dis. 2015;1(12):615-626.
2016 Bavetsias V, Lanigan RM, Ruda GF, et al. 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J Med Chem. 2016;59(4):1388-1409.

 

 

For more information on this register please email GSKClinicalSupportHD@gsk.com

GSK-sponsored clinical studies are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party.
GSK-sponsored clinical trials are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party.

ClinicalTrial.gov is a database that provides summary protocol information for ongoing clinical trials.

IFPMA.org is a search portal provided by the International Federation of Pharamceutical Manufacturers & Associations (IFPMA).

This portal provides a single entry point to search for industry sponsored clinical trials which are on existing registers and databases.

EU Clinical Trials Register is a database of all clinical trials commencing in the European Community from 1 May 2004 onwards. It has been established in accordance with Directive 2001/20/EC.