Pre-Clinical Publications

 

This section of the GSK study register provides citations from pre-clinical research where there is a GSK author. Please note that there may be other publications that are not listed here.

To find citations, enter a key word into the Citation Text Search field and/or enter a Publication Year.

 

 

Publication Year Citation
2018 Annibaldi A, Wicky John S, Vanden Berghe T, et al. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Mol Cell. 2018;69(4):566-580 e565.
2018 Blakemore DC, Castro L, Churcher I, et al. Organic synthesis provides opportunities to transform drug discovery. Nat Chem. 2018;10(4):383-394.
2018 Brown KK, Hann MM, Lakdawala AS, Santos R, Thomas PJ, Todd K. Approaches to target tractability assessment – a practical perspective. MedChemComm. 2018;9(4):606-613.
2018 Bueno JM, Calderon F, Chicharro J, et al. Synthesis and Structure-Activity Relationships of the Novel Antimalarials 5-Pyridinyl-4(1 H)-Pyridones. J Med Chem. 2018;61(8):3422-3435.
2018 Caltabiano AM, Foley JP, Striegel AM. Aqueous size-exclusion chromatography of polyelectrolytes on reversed-phase and hydrophilic interaction chromatography columns. Journal of chromatography A. 2018;1532:161-174.
2018 Caltabiano AM, Foley JP, Striegel AM. Organic solvent modifier and temperature effects in non-aqueous size-exclusion chromatography on reversed-phase columns. Journal of chromatography A. 2018;1531:83-103.
2018 Campbell IB, Macdonald SJF, Procopiou PA. Medicinal chemistry in drug discovery in big pharma: past, present and future. Drug Discov Today. 2018;23(2):219-234.
2018 Carroll RG, Zaslona Z, Galvan-Pena S, et al. An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation. The Journal of biological chemistry. 2018;293(15):5509-5521.
2018 Castellanos MM, Howell SC, Gallagher DT, Curtis JE. Characterization of the NISTmAb Reference Material using small-angle scattering and molecular simulation : Part I: Dilute protein solutions. Anal Bioanal Chem. 2018;410(8):2141-2159.
2018 Castellanos MM, Mattison K, Krueger S, Curtis JE. Characterization of the NISTmAb Reference Material using small-angle scattering and molecular simulation : Part II: Concentrated protein solutions. Anal Bioanal Chem. 2018;410(8):2161-2171.
2018 Chen H, Kankel MW, Su SC, Han SWS, Ofengeim D. Exploring the genetics and non-cell autonomous mechanisms underlying ALS/FTLD. Cell Death Differ. 2018;25(4):646-660.
2018 Cheung M, Tangirala RS, Bethi SR, et al. Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. ACS Med Chem Lett. 2018;9(2):103-108.
2018 Ching T, Himmelstein DS, Beaulieu-Jones BK, et al. Opportunities and obstacles for deep learning in biology and medicine. J R Soc Interface. 2018;15(141).
2018 Cortada-Garcia M, Weheliye WH, Dore V, Mazzei L, Angeli P. Computational fluid dynamic studies of mixers for highly viscous shear thinning fluids and PIV validation. Chemical Engineering Science. 2018;179:133-149.
2018 Cribbs A, Hookway ES, Wells G, et al. Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells. The Journal of biological chemistry. 2018;293(7):2422-2437.
2018 Dalton SE, Dittus L, Thomas DA, et al. Selectively Targeting the Kinome-Conserved Lysine of PI3Kdelta as a General Approach to Covalent Kinase Inhibition. J Am Chem Soc. 2018;140(3):932-939.
2018 Deaton DN, Haffner CD, Henke BR, et al. 2,4-Diamino-8-quinazoline carboxamides as novel, potent inhibitors of the NAD hydrolyzing enzyme CD38: Exploration of the 2-position structure-activity relationships. Bioorganic & medicinal chemistry. 2018;26(8):2107-2150
2018 Ding H, Douglass EF, Jr., Sonabend AM, et al. Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm. Nat Commun. 2018;9(1):1471.
2018 Donovan BT, Bandyopadhyay D, Duraiswami C, Nixon CJ, Townsend CY, Martens SF. Discovery and electrophysiological characterization of SKF-32802: A novel hERG agonist found through a large-scale structural similarity search. Eur J Pharmacol. 2018;818:306-327
2018 Edney D, Hulcoop DG, Leahy JH, et al. Development of Flexible and Scalable Routes to Two Phosphatidinylinositol-3-kinase Delta Inhibitors via a Common Intermediate Approach. Organic Process Research & Development. 2018;22(3):368-376.
2018 Ferdous MM, Bao Y, Vinciotti V, Liu X, Wilson P. Predicting gene expression from genome wide protein binding profiles. Neurocomputing. 2018;275:1490-1499.
2018 Gillis WF, Lissandrello CA, Shen J, et al. Carbon fiber on polyimide ultra-microelectrodes. J Neural Eng. 2018;15(1):016010.
2018 Gooris GS, Kamran M, Kros A, Moore DJ, Bouwstra JA. Interactions of dipalmitoylphosphatidylcholine with ceramide-based mixtures. Biochimica et biophysica acta. 2018;1860(6):1272-1281.
2018 Griffiths RJ, Kong WC, Richards SA, Burley GA, Willis MC, Talbot EPA. Oxidative beta-C-H sulfonylation of cyclic amines. Chem Sci. 2018;9(8):2295-2300.
2018 Hartkamp R, Moore TC, Iacovella CR, et al. Composition Dependence of Water Permeation Across Multicomponent Gel-Phase Bilayers. J Phys Chem B. 2018;122(12):3113-3123.

 

 

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