Pre-Clinical Publications


This section of the GSK study register provides citations from pre-clinical research where there is a GSK author. Please note that there may be other publications that are not listed here.

To find citations, enter a key word into the Citation Text Search field and/or enter a Publication Year.



Publication Year Citation
2016 Caballero I, Lafuente MJ, Gamo FJ, Cid C. A high-throughput fluorescence-based assay for Plasmodium dihydroorotate dehydrogenase inhibitor screening. Anal Biochem. 2016;506:13-21.
2016 Shankaran M, Shearer TW, Stimpson SA, et al. Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats. Am J Physiol Endocrinol Metab. 2016;310(6):E405-417.
2016 Pennell MN, Kyle MP, Gibson SM, et al. Intercepting the Gold-Catalysed Meyer-Schuster Rearrangement by Controlled Protodemetallation: A Regioselective Hydration of Propargylic Alcohols. Advanced Synthesis & Catalysis. 2016;358(9):1519-1525.
2016 Kost TA, Kemp CW. Fundamentals of Baculovirus Expression and Applications. Adv Exp Med Biol. 2016;896:187-197.
2016 Yu HB, Zou BY, Wang XL, Li M. Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay. Acta Pharmacol Sin. 2016;37(1):111-123.
2016 Xie F, Ding X, Zhang QY. An update on the role of intestinal cytochrome P450 enzymes in drug disposition. Acta Pharm Sin B. 2016;6(5):374-383.
2016 PĂ©rez B, Bulsara P, Rawlings AV, et al. Ultralong Fatty Acyl Derivatives As Occlusive Structure Lipids for Cosmetic Applications: Synthesis and Characterization. ACS Sustainable Chemistry & Engineering. 2016;4(12):7137-7146.
2016 Longo LS, Smith EF, Licence P. Study of the Stability of 1-Alkyl-3-methylimidazolium Hexafluoroantimonate(V) Based Ionic Liquids Using X-ray Photoelectron Spectroscopy. ACS Sustainable Chemistry & Engineering. 2016;4(11):5953-5962.
2016 Xu H, Lu H, Xu Z, et al. Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders. ACS Med Chem Lett. 2016;7(4):397-402.
2016 Pero JE, Rossi MA, Kelly MJ, 3rd, et al. Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. ACS Med Chem Lett. 2016;7(3):312-317.
2016 Lin H, Zeng J, Xie R, et al. Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors. ACS Med Chem Lett. 2016;7(3):217-222.
2016 Handlon AL, Schaller LT, Leesnitzer LM, et al. Optimizing Ligand Efficiency of Selective Androgen Receptor Modulators (SARMs). ACS Med Chem Lett. 2016;7(1):83-88.
2016 Deng H, Zhou J, Sundersingh F, et al. Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors. ACS Med Chem Lett. 2016;7(4):379-384.
2016 Kumar A, Guardia A, Colmenarejo G, et al. A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis. ACS Infect Dis. 2015;1(12):604-614.
2016 Batt SM, Cacho Izquierdo M, Castro Pichel J, et al. Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-beta-d-ribose Oxidase. ACS Infect Dis. 2015;1(12):615-626.
2016 Amata E, Xi H, Colmenarejo G, et al. Identification of "Preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing? ACS Infect Dis. 2016;2(3):180-186.
2016 Haftchenary S, Nelson SD, Jr., Furst L, et al. Efficient Routes to a Diverse Array of Amino Alcohol-Derived Chiral Fragments. ACS Comb Sci. 2016;18(9):569-574.
2016 Ding Y, Franklin GJ, DeLorey JL, et al. Design and Synthesis of Biaryl DNA-Encoded Libraries. ACS Comb Sci. 2016;18(10):625-629.
2016 Rutkowska A, Thomson DW, Vappiani J, et al. A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level. ACS Chem Biol. 2016;11(9):2541-2550.
2016 Joberty G, Boesche M, Brown JA, et al. Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics. ACS Chem Biol. 2016;11(7):2002-2010.
2016 Billin AN, Bantscheff M, Drewes G, et al. Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle. ACS Chem Biol. 2016;11(2):518-529.
2016 MacNair AJ, Millet CRP, Nichol GS, Ironmonger A, Thomas SP. Markovnikov-Selective, Activator-Free Iron-Catalyzed Vinylarene Hydroboration. ACS Catalysis. 2016;6(10):7217-7221.
2016 Mayer AP, Hottenstein CS. Ligand-Binding Assay Development: What Do You Want to Measure Versus What You Are Measuring? AAPS J. 2016;18(2):287-289.
2016 Rovati L, Cattini S, Crespi F. Near-infrared spectroscopy for non-invasive monitoring of drugs blood-brain barrier penetration. IEEE Instrumentation and Measurement Technology Conference 2016: 7520564
2016 Miller RA, Melius J, Nunes N, Willighagen EL, Woollard P, Evelo CT. Finding drugs with common downstream effects, using direction information in biological pathways. CEUR Workshop Proceedings 2016: 1795



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